GRIK1 polyclonal antibody
产品名称： GRIK1 polyclonal antibody
英文名称： GRIK1 polyclonal antibody
产品编号： PAB7354
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of GRIK1.
- Immunogen:
- A synthetic peptide corresponding to human GRIK1.
- Sequence:
- QCKQTHPTNSTS
- Host:
- Goat
- Theoretical MW (kDa):
- 104, 103
- Reactivity:
- Human
- Specificity:
- This antibody is expected to recognize both reported isoforms according to NP_000821.1 and NP_783300.1.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:8000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- SUMOylation regulates kainate-receptor-mediated synaptic transmission.
Martin S, Nishimune A, Mellor JR, Henley JM.Nature. 2007 May 17;447(7142):321-5. Epub 2007 May 7.
- Entrez GeneID:
- 2897
- Protein Accession#:
- NP_000821.1;NP_783300.1
- Gene Name:
- GRIK1
- Gene Alias:
- EAA3,EEA3,GLR5,GLUR5
- Gene Description:
- glutamate receptor, ionotropic, kainate 1
- Omim ID:
- 138245
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000096569,excitatory amino acid receptor 3,glutamate receptor 5
- Gene Pathway