Cathepsin G,组织蛋白酶G抗体

产品编号HZ-1598R
英文名称Cathepsin G
中文名称组织蛋白酶G抗体
别 名CTSG; Cathepsin G; CG; Cathepsin G precursor; CathepsinG; CTSG; CTSG protein; MGC23078; CATG_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 合成与降解
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
Cathepsin G,组织蛋白酶G抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量28kDa
细胞定位细胞膜 细胞外基质
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CTSG
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Cathepsin G,组织蛋白酶G抗体PubMedPubMed
产品介绍background:
Cathepsin G is a serine protease, it consisting of a single polypeptide with a molecular weight of 30 kDa as determined by SDS-PAGE. Its substrates are collagen and proteoglycans. Poor regulation of Cathepsin G levels has been associated with various connective tissue disorders, for example pulmonary emphysema and cystic fibrosis.

Function:
Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe-CH2Cl and phenylmethylsulfonyl fluoride.

Subcellular Location:
Cell surface.

Similarity:
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.

Gene ID:
1511

Cathepsin G,组织蛋白酶G抗体Database links:
Entrez Gene: 1511 Human
Omim: 116830 Human
SwissProt: P08311 Human
Unigene: 421724 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.